Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Hypoxia
ADR ID BADD_A02233
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.02      Respiratory disorders NEC
22.02.02      Conditions associated with abnormal gas exchange
22.02.02.003      Hypoxia
Description A disorder characterized by a decrease in the level of oxygen in the body. [CTCAE] Sub-optimal OXYGEN levels in the ambient air of living organisms. | Relatively complete absence of oxygen in one or more tissues. [MeSH]
MedDRA Code 10021143
MeSH ID D000860; D000860; D000860
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Alveolar aeration decreased | Hypoxaemia | Hypoxemia | Hypoxia | Hypoxic | Oxygen Deficiency | Deficiency, Oxygen | Deficiencies, Oxygen | Oxygen Deficiencies | Anoxia | Anoxemia
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
CCAAT/enhancer-binding protein epsilonQ6PZD9Not Available
NADH-cytochrome b5 reductase 3P00387Not Available
NADPH--cytochrome P450 reductaseP16435T95446
Sulfotransferase 1B1O43704Not Available
Sulfotransferase 1B1P52847Not Available
UDP-glucuronosyltransferase 2B15P54855Not Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01649Oxymorphone hydrochloride--
BADD_D01653Paclitaxel0.004529%
BADD_D01654Palbociclib--
BADD_D01659Palonosetron--
BADD_D01668Pantoprazole--
BADD_D01701Pemetrexed0.000799%
BADD_D01710Penicillin g--
BADD_D01711Penicillin g benzathine--
BADD_D01726Pentobarbital--
BADD_D01734Perflutren--
BADD_D01735Pergolide--
BADD_D01736Pergolide mesylate--
BADD_D01751Phenelzine sulfate--
BADD_D01752Phenobarbital--
BADD_D01765Phenytoin--
BADD_D01783Pirfenidone0.002417%
BADD_D01798Pomalidomide--
BADD_D01799Ponatinib0.001332%
BADD_D01822Prasugrel0.000460%
BADD_D01834Prednisone0.000438%
BADD_D01835Pregabalin--
BADD_D01836Prilocaine--
BADD_D01848Prochlorperazine0.001046%
BADD_D01854Promethazine0.002785%
BADD_D01858Propagermanium--
BADD_D01864Propofol0.006699%
BADD_D01867Propranolol0.001139%
BADD_D01881Pyridostigmine0.009740%
BADD_D01888Quetiapine0.002802%
BADD_D01898Rabeprazole--
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